General Information

  • ID:  hor002487
  • Uniprot ID:  NA
  • Protein name:  SALMFamide
  • Gene name:  NA
  • Organism:  Holothuria glaberrima
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SGYSVLYF
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T8 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002487_AF2.pdbhor002487_ESM.pdb

Physical Information

Mass: 106007 Formula: C46H62N8O13
Absent amino acids: ACDEHIKMNPQRTW Common amino acids: SY
pI: 6.09 Basic residues: 0
Polar residues: 5 Hydrophobic residues: 3
Hydrophobicity: 77.5 Boman Index: 580
Half-Life / Aliphatic Index: 1.9 hour Aliphatic Index: 85
Instability Index: -186.25 Extinction Coefficient cystines: 2980
Absorbance 280nm: 425.71

Literature

  • PubMed ID:  7722004
  • Title:  Localization of the Heptapeptide GFSKLYFamide in the Sea Cucumber Holothuria Glaberrima (Echinodermata): A Light and Electron Microscopic Study